Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 12 Researches
8.1
USERS' SCORE
Good
Based on 9 Reviews
8.5
Supplement Facts
Serving Size: 1 Veggie Capsule
Amount Per Serving
%DV
Selenium (from SelenoExcell® High Selenium Yeast) (Saccharomyces cerevisiae)
50 mcg
90%
Molybdenum (from molybdenum glycinate chelate)
50 mcg
110%
N-Acetylcysteine (NAC)
600 mg
†
Top Medical Research Studies
9
Postbiotic reduces Salmonella in pullets
We evaluated how a postbiotic derived from Saccharomyces cerevisiae might help reduce Salmonella Enteritidis in young layer pullets. In our study, we tested two groups of pullets—one group received a diet supplemented with the postbiotic, while the other did not.
After introducing the bacteria, we found that while all birds had Salmonella presence, those on the postbiotic diet had significantly lower levels of the bacteria. This suggests that including Saccharomyces cerevisiae could offer an effective strategy for enhancing food safety before harvest.
After introducing the bacteria, we found that while all birds had Salmonella presence, those on the postbiotic diet had significantly lower levels of the bacteria. This suggests that including Saccharomyces cerevisiae could offer an effective strategy for enhancing food safety before harvest.
Read More
9
We explored the protective effects of selenium nanoparticles (SeNPs) against the harmful impacts of zearalenone (ZEA), a toxin from grains that can disrupt gut health. In a controlled setting, we observed that ZEA damages intestinal cells, leading to inflammation and increased permeability.
Our findings showed that SeNPs can counteract this damage by enhancing antioxidant activity and improving gut microbiota balance. Despite these promising results, it’s crucial to note that the effectiveness of SeNPs in humans still requires further investigation.
Our findings showed that SeNPs can counteract this damage by enhancing antioxidant activity and improving gut microbiota balance. Despite these promising results, it’s crucial to note that the effectiveness of SeNPs in humans still requires further investigation.
Read More
8
We investigated whether selenium has a protective effect against the harmful impacts of aflatoxin B (AFB), a common toxin found in food. By studying broiler chickens over three weeks, we set up different groups to see how selenium influences cell death caused by AFB.
Our findings showed that selenium supplementation significantly reduced excess cell death in the jejunum, helping restore key biological markers to healthier levels. This research helps highlight selenium's potential as a protective agent against food-related poisonings.
Our findings showed that selenium supplementation significantly reduced excess cell death in the jejunum, helping restore key biological markers to healthier levels. This research helps highlight selenium's potential as a protective agent against food-related poisonings.
Read More
Most Useful Reviews
9
Clearer skin
82 people found this helpful
I noticed my son's sweat was turning yellow, possibly due to excess toxins from fast food. I bought him these capsules and after consistent use, it’s remarkable! His skin has cleared up, and the unpleasant odour has gone. Truly, they are wonderful for detoxifying the body.
Read More
10
Improved health
2 people found this helpful
Best one for food allergies! My health has improved consistently after consuming this over four months.
Read More
9
Always in first-aid
1 people found this helpful
Always found in my first aid kit, this is the best amino acid for poisoning. It serves as an essential first aid for feeling unwell.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 12 Researches
8.1
- All Researches
9
Postbiotic reduces Salmonella in pullets
We evaluated how a postbiotic derived from Saccharomyces cerevisiae might help reduce Salmonella Enteritidis in young layer pullets. In our study, we tested two groups of pullets—one group received a diet supplemented with the postbiotic, while the other did not.
After introducing the bacteria, we found that while all birds had Salmonella presence, those on the postbiotic diet had significantly lower levels of the bacteria. This suggests that including Saccharomyces cerevisiae could offer an effective strategy for enhancing food safety before harvest.
After introducing the bacteria, we found that while all birds had Salmonella presence, those on the postbiotic diet had significantly lower levels of the bacteria. This suggests that including Saccharomyces cerevisiae could offer an effective strategy for enhancing food safety before harvest.
Read More
9
We explored how Saccharomyces cerevisiae RC016 could benefit gut health and growth in weaned piglets. Through a well-structured study, we divided twelve piglets into two groups: one received the yeast, while the other served as a control. After three weeks, results showed the yeast group had higher levels of protective antibodies and more goblet cells, indicating better gut health. An additional ex vivo model suggested that the yeast may also help reduce inflammation. Overall, S. cerevisiae RC016 shows promise as a feed additive that can enhance animal welfare and immunity.
Read More
9
We explored the protective effects of selenium nanoparticles (SeNPs) against the harmful impacts of zearalenone (ZEA), a toxin from grains that can disrupt gut health. In a controlled setting, we observed that ZEA damages intestinal cells, leading to inflammation and increased permeability.
Our findings showed that SeNPs can counteract this damage by enhancing antioxidant activity and improving gut microbiota balance. Despite these promising results, it’s crucial to note that the effectiveness of SeNPs in humans still requires further investigation.
Our findings showed that SeNPs can counteract this damage by enhancing antioxidant activity and improving gut microbiota balance. Despite these promising results, it’s crucial to note that the effectiveness of SeNPs in humans still requires further investigation.
Read More
8
Yeast reduces Salmonella in vitro
We explored how various yeast-derived products could impact Salmonella Enteritidis survival in rooster cecal contents during in vitro tests. Several yeast treatments showed promise, with four products significantly reducing Salmonella levels by 1 log CFU/mL initially and by 3 log CFU/mL after 48 hours, compared to controls.
However, these treatments did not influence the overall diversity or health of the cecal microbiome, indicating that beneficial effects can occur without disrupting the gut environment. This research underscores the potential of yeast products in combating foodborne pathogens while maintaining gut balance.
However, these treatments did not influence the overall diversity or health of the cecal microbiome, indicating that beneficial effects can occur without disrupting the gut environment. This research underscores the potential of yeast products in combating foodborne pathogens while maintaining gut balance.
Read More
8
We investigated how feeding layer chicks with a combination of dietary direct-fed microbial and yeast cell walls affects their response to Salmonella Enteritidis, a common cause of food poisoning.
The study involved 160 chicks divided into control and treatment groups. Chicks in the treatment group showed a significantly lower prevalence of Salmonella and a richer diversity of beneficial bacteria in their gut over time. These findings suggest that this dietary supplement can help reduce food poisoning risk and enhance gut health in poultry.
This approach might be valuable in managing foodborne pathogens more effectively.
The study involved 160 chicks divided into control and treatment groups. Chicks in the treatment group showed a significantly lower prevalence of Salmonella and a richer diversity of beneficial bacteria in their gut over time. These findings suggest that this dietary supplement can help reduce food poisoning risk and enhance gut health in poultry.
This approach might be valuable in managing foodborne pathogens more effectively.
Read More
User Reviews
USERS' SCORE
Good
Based on 9 Reviews
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
9
Clearer skin
82 people found this helpful
I noticed my son's sweat was turning yellow, possibly due to excess toxins from fast food. I bought him these capsules and after consistent use, it’s remarkable! His skin has cleared up, and the unpleasant odour has gone. Truly, they are wonderful for detoxifying the body.
Read More
10
Improved health
2 people found this helpful
Best one for food allergies! My health has improved consistently after consuming this over four months.
Read More
9
Always in first-aid
1 people found this helpful
Always found in my first aid kit, this is the best amino acid for poisoning. It serves as an essential first aid for feeling unwell.
Read More
7.5
Boosted antioxidant levels
9 people found this helpful
I feel an improvement after taking NAC, which supports detoxification and aids in synthesising glutathione—the main antioxidant. Buying a non-liposomal glutathione isn’t worth it, so NAC seems to be beneficial. I take it twice daily with meals, and the addition of selenium and molybdenum further supports my health. Happy to help!
Read More
6
Feeling better overall
6 people found this helpful
After about a month of drinking it, I began to feel the difference in my physical condition. The work I do is quite sedentary, which likely resulted in self-poisoning. However, I felt noticeably improved after starting this treatment.
Read More
Frequently Asked Questions
6
Feeling better overall
6 people found this helpful
After about a month of drinking it, I began to feel the difference in my physical condition. The work I do is quite sedentary, which likely resulted in self-poisoning. However, I felt noticeably improved after starting this treatment.
10
Improved health
2 people found this helpful
Best one for food allergies! My health has improved consistently after consuming this over four months.
9
Essential for emergencies
4 people found this helpful
NAC capsules are a must-have in every home for emergency use in cases of poisoning until medical care is available. One significant benefit is that it protects the liver and increases glutathione levels, the body’s most powerful antioxidant.
9
Clearer skin
82 people found this helpful
I noticed my son's sweat was turning yellow, possibly due to excess toxins from fast food. I bought him these capsules and after consistent use, it’s remarkable! His skin has cleared up, and the unpleasant odour has gone. Truly, they are wonderful for detoxifying the body.
6
Improved digestion
2 people found this helpful
As I’ve aged, I've experienced food-related stomach issues, leading to gas and phlegm. Taking NAC has helped prevent these problems. Its slight saltiness isn’t unpleasant, making it an easy addition to my routine.
7.5
Boosted antioxidant levels
9 people found this helpful
I feel an improvement after taking NAC, which supports detoxification and aids in synthesising glutathione—the main antioxidant. Buying a non-liposomal glutathione isn’t worth it, so NAC seems to be beneficial. I take it twice daily with meals, and the addition of selenium and molybdenum further supports my health. Happy to help!
7.5
Effective toxin removal
1 people found this helpful
The quality of this product is excellent. It includes citric acid to help eliminate toxins while supporting liver function. It’s suitable as a dietary supplement, and the packaging is impressive. I recommend consulting a doctor before use.
7
We explored the effects of the probiotic CNCM I-3856 on the enterotoxigenic E. coli (ETEC), a common cause of traveler's diarrhea.
Using advanced gut models, we found that while the probiotic didn’t stop ETEC from surviving in the digestive tract, it significantly decreased the bacteria's ability to produce harmful enterotoxins.
Over 18 days, the treatment also promoted beneficial microbial growth and increased short-chain fatty acids, which are good for gut health. Our results highlight the potential of CNCM I-3856 as a preventive measure against ETEC infections.
Using advanced gut models, we found that while the probiotic didn’t stop ETEC from surviving in the digestive tract, it significantly decreased the bacteria's ability to produce harmful enterotoxins.
Over 18 days, the treatment also promoted beneficial microbial growth and increased short-chain fatty acids, which are good for gut health. Our results highlight the potential of CNCM I-3856 as a preventive measure against ETEC infections.
8
Yeast reduces Salmonella in vitro
We explored how various yeast-derived products could impact Salmonella Enteritidis survival in rooster cecal contents during in vitro tests. Several yeast treatments showed promise, with four products significantly reducing Salmonella levels by 1 log CFU/mL initially and by 3 log CFU/mL after 48 hours, compared to controls.
However, these treatments did not influence the overall diversity or health of the cecal microbiome, indicating that beneficial effects can occur without disrupting the gut environment. This research underscores the potential of yeast products in combating foodborne pathogens while maintaining gut balance.
However, these treatments did not influence the overall diversity or health of the cecal microbiome, indicating that beneficial effects can occur without disrupting the gut environment. This research underscores the potential of yeast products in combating foodborne pathogens while maintaining gut balance.
9
Postbiotic reduces Salmonella in pullets
We evaluated how a postbiotic derived from Saccharomyces cerevisiae might help reduce Salmonella Enteritidis in young layer pullets. In our study, we tested two groups of pullets—one group received a diet supplemented with the postbiotic, while the other did not.
After introducing the bacteria, we found that while all birds had Salmonella presence, those on the postbiotic diet had significantly lower levels of the bacteria. This suggests that including Saccharomyces cerevisiae could offer an effective strategy for enhancing food safety before harvest.
After introducing the bacteria, we found that while all birds had Salmonella presence, those on the postbiotic diet had significantly lower levels of the bacteria. This suggests that including Saccharomyces cerevisiae could offer an effective strategy for enhancing food safety before harvest.
8
We explored the potential of selenium-enriched Kazachstania unispora KU2 in alleviating intestinal injuries caused by the foodborne toxin patulin (PAT). Our investigation revealed that both the standard K. unispora and its selenium-enriched version helped reduce inflammation and restore gut health.
Interestingly, the selenium-enriched variant showed even greater effectiveness. It seemed to work by enhancing the production of a specific protein, SEPP1. We verified that a healthy gut microbiota was essential for these positive effects. This study hints at promising treatment options for intestinal diseases linked to foodborne toxins.
Interestingly, the selenium-enriched variant showed even greater effectiveness. It seemed to work by enhancing the production of a specific protein, SEPP1. We verified that a healthy gut microbiota was essential for these positive effects. This study hints at promising treatment options for intestinal diseases linked to foodborne toxins.
References
- Costello M, Rubinelli P, Brown J, Olson E, Dittoe D, et al. Comparison of yeast-derived commercial feed additives on Salmonella Enteritidis survival and microbiota populations in rooster cecal in vitro incubations. PLoS One. 2023;18:e0295657. 10.1371/journal.pone.0295657
- Roussel C, De Paepe K, Galia W, de Bodt J, Chalancon S, et al. Multi-targeted properties of the probiotic CNCM I-3856 against enterotoxigenic (ETEC) H10407 pathogenesis across human gut models. Gut Microbes. 2021;13:1953246. 10.1080/19490976.2021.1953246
- Suganuma K, Hamasaki T, Hamaoka T. Effect of dietary direct-fed microbial and yeast cell walls on cecal digesta microbiota of layer chicks inoculated with nalidixic acid resistant Salmonella Enteritidis. Poult Sci. 2021;100:101385. 10.1016/j.psj.2021.101385
- Gingerich E, Frana T, Logue CM, Smith DP, Pavlidis HO, et al. Effect of Feeding a Postbiotic Derived from Saccharomyces cerevisiae Fermentation as a Preharvest Food Safety Hurdle for Reducing Salmonella Enteritidis in the Ceca of Layer Pullets. J Food Prot. 2021;84:275. 10.4315/JFP-20-330
- Girgis G, Powell M, Youssef M, Graugnard DE, King WD, et al. Effects of a mannan-rich yeast cell wall-derived preparation on cecal concentrations and tissue prevalence of Salmonella Enteritidis in layer chickens. PLoS One. 2020;15:e0232088. 10.1371/journal.pone.0232088
- Garcia GR, Dogi CA, Poloni VL, Fochesato AS, De Moreno de Leblanc A, et al. Beneficial effects of Saccharomyces cerevisiae RC016 in weaned piglets: in vivo and ex vivo analysis. Benef Microbes. 2019;10:33. 10.3920/BM2018.0023
- Badia R, Brufau MT, Guerrero-Zamora AM, Lizardo R, Dobrescu I, et al. β-Galactomannan and Saccharomyces cerevisiae var. boulardii modulate the immune response against Salmonella enterica serovar Typhimurium in porcine intestinal epithelial and dendritic cells. Clin Vaccine Immunol. 2012;19:368. 10.1128/CVI.05532-11
- Price KL, Totty HR, Lee HB, Utt MD, Fitzner GE, et al. Use of Saccharomyces cerevisiae fermentation product on growth performance and microbiota of weaned pigs during Salmonella infection. J Anim Sci. 2010;88:3896. 10.2527/jas.2009-2728
- Wang F, Wang X, Xiao Y, Liu R, Li X, et al. Selenium-enriched Kazachstania unispora KU2 ameliorates patulin-induced intestinal injury in mice by mediating the gut microbiota and selenoprotein P synthesis. J Hazard Mater. 2025;492:138129. 10.1016/j.jhazmat.2025.138129
- Qiao L, Chang J, Yang G, Deng T, Liu P, et al. Prophylactic supplementation with selenium nanoparticles protects against foodborne toxin zearalenone-induced intestinal barrier dysfunction. Ecotoxicol Environ Saf. 2024;284:116914. 10.1016/j.ecoenv.2024.116914
- Liu Y, Dong R, Yang Y, Xie H, Huang Y, et al. Protective Effect of Organic Selenium on Oxidative Damage and Inflammatory Reaction of Rabbit Kidney Induced by T-2 Toxin. Biol Trace Elem Res. 2021;199:1833. 10.1007/s12011-020-02279-5
- Fang J, Zheng Z, Yang Z, Peng X, Zuo Z, et al. Ameliorative effects of selenium on the excess apoptosis of the jejunum caused by AFB through death receptor and endoplasmic reticulum pathways. Toxicol Res (Camb). 2018;7:1108. 10.1039/c8tx00068a
